FIGURE 4.

Gray matter regions where the volume was associated with body mass index (BMI), overweight or obese, and obese women. (A) BMI was negatively correlated with gray matter volumes in the bilateral cerebellum exterior [p < 0.01 corrected, Montreal Neurological Institute (MNI) 152 T1 atlas coordinates: x = −30.0 mm, y = −93.0 mm, z = −31.5 mm indicated by blue cross-hair lines]. (B) Gray matter volume in the right cerebellum exterior was reduced in overweight or obese women when compared with that in underweight or normal men (p < 0.05 corrected, MNI 152 T1 atlas coordinates: x = 9.0 mm, y = −84.0 mm, z = −51.0 mm indicated by blue cross-hair lines). (C) Gray matter volume in the left cerebellum exterior was reduced in obese women when compared with that in non-obese women (p < 0.01 corrected, MNI 152 T1 atlas coordinates: x = −21.0 mm, y = −94.5 mm, z = −30.0 mm indicated by blue cross-hair lines). Right-sided gradient color bars represent t-scores. a, anterior; l, left; p, posterior; r, right.