Table 1.

Lead time of normalized IAV viral RNA signal to weekly IAV percent positivity.

Outbreak progression	Lead time of wastewater to clinical metric	Details
First detection	17 days	WWS: IAV in population first identified Clinical: IAV in population first identified
Outbreak detection	21 days	WWS: First 3 consecutive days of increasing IAV viral signal Clinical: First 2 consecutive weeks of increasing weekly percent positivity
Peak of outbreak	15 days	WWS: Date of highest 7-day midpoint avg. IAV viral signal Clinical: Date of highest percent positivity
Outbreak resolution	17 days	WWS: 7 consecutive days of decreasing 7-day midpoint avg. IAV viral signal Clinical: 2 consecutive weeks of decreasing weekly percent positivity