TABLE 1.
Baseline characteristics in CAD/non-CAD groups.
| Variables | Total n = 152 | Non-CAD n = 75 | CAD n = 77 | P-value |
| Demographics | ||||
| Age, years | 65.0 ± 11.4 | 64.8 ± 12.8 | 65.2 ± 10.0 | 0.854 |
| Male, n (%) | 85 (55.9) | 38 (50.7) | 47 (61.0) | 0.198 |
| BMI, kg/m2 | 24.56 ± 3.49 | 24.47 ± 3.33 | 24.65 ± 3.66 | 0.751 |
| SBP, mmHg | 143.73 ± 22.64 | 143.37 ± 23.47 | 144.08 ± 21.94 | 0.849 |
| DBP, mmHg | 81.76 ± 12.96 | 80.64 ± 13.38 | 82.847 ± 12.53 | 0.296 |
| Comorbidities, n (%) | ||||
| DM | 38 (25.0) | 13 (17.3) | 25 (32.5) | 0.031 |
| Smoking | 32 (21.1) | 12 (16.0) | 20 (26.0) | 0.132 |
| Hypertension | 98 (64.5) | 46 (61.3) | 52 (67.5) | 0.425 |
| Hyperlipidemia | 16 (10.5) | 7 (9.3) | 9 (11.7) | 0.636 |
| Stroke | 20 (13.2) | 10 (13.3) | 10 (13.0) | 0.950 |
| Medications, n (%) | ||||
| Statin | 23 (15.1) | 4 (5.3) | 19 (24.7) | 0.001 |
| ACEI/ARB | 22 (14.5) | 11 (14.7) | 11 (14.3) | 0.947 |
| CCB | 27 (17.8) | 12 (16.0) | 15 (19.5) | 0.575 |
| β-Blocker | 8 (5.3) | 5 (6.7) | 3 (3.9) | 0.492 |
| Laboratory data | ||||
| LVEF, % | 64.13 ± 8.31 | 64.72 ± 7.02 | 63.56 ± 9.41 | 0.391 |
| Pro-BNP | 124 (50–299) | 124 (47–295) | 124 (57–303) | 0.666 |
| TC, mmol | 4.53 ± 1.08 | 4.64 ± 1.02 | 4.42 ± 1.14 | 0.217 |
| TG, mmol/L | 1.47 (1.07–1.99) | 1.36 (1.02–1.91) | 1.55 (1.14–2.02) | 0.191 |
| HDL-C, mmol/L | 1.13 ± 0.30 | 1.16 ± 0.29 | 1.09 ± 0.30 | 0.137 |
| LDL-C, mmol/L | 2.53 (1.98–2.98) | 2.6 (2.10–2.98) | 2.40 (1.94–2.96) | 0.122 |
| FPG, mmol/L | 5.2 (4.8–6.1) | 5.2 (4.7–5.7) | 5.3 (4.8–6.4) | 0.126 |
| HbA1c, mmol/L | 6.0 (5.5–6.3) | 6.0 (5.4–6.2) | 6.00 (5.6–6.8) | 0.141 |
| HsCRP, mg/L | 3.5 (3.3–7.9) | 3.3 (3.3–5.2) | 5.2 (3.3–11.7) | 0.001 |
| AST, U/L | 18 (15–24) | 18 (15–22) | 20 (17–25) | 0.101 |
| ALT, U/L | 18 (12–26) | 16 (12–23) | 19 (14–26) | 0.165 |
| BUN, mmol/L | 5.92 ± 2.12 | 5.79 ± 2.35 | 6.04 ± 1.87 | 0.461 |
| Creatinine, mg/L | 78.5 (67.0–91.0) | 75.0 (63.0–87.9) | 81.0 (71.5–95.5) | 0.043 |
| Uric acid, mg/L | 351.69 ± 100.39 | 334.65 ± 98.42 | 368.30 ± 100.12 | 0.038 |
| Adiponectin, mg/mL | 11.40 ± 8.31 | 11.15 ± 7.25 | 11.64 ± 9.27 | 0.717 |
| Chemerin, ng/mL | 119.52 ± 33.95 | 109.85 ± 27.47 | 128.93 ± 37.06 | <0.001 |
Values are mean ± standard deviation, median (interquartile range), or n (%). CAD, coronary artery disease; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; n, number of patients; DM, diabetes mellitus; ACEI/ARB, angiotensin-converting enzyme inhibitor and angiotensin receptor blocker; CCB, calcium channel blocker; LVEF, left ventricular ejection fraction; Pro-BNP, pro-brain natriuretic peptide; TC, total cholesterol; TG: Triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; FPG, fasting plasma glucose; HbA1c, Hemoglobin A1c; AST, aspartate transaminase; BUN, blood urine nitrogen; hsCRP, high sensitivity C-reactive protein.