TABLE 5.

Gene Ontology (GO), biological processes (BP) analysis for the top gene targets of piRNAs (time point, RSV 24 h p.i) with p values <0.01 or <0.05

Biological process (BP)	Fold enrichment
Golgi organization (GO:0007030)	3.29
activation of GTPase activity (GO:0090630)	2.94
endosomal transport (GO:0016197)	2.11
regulation of small GTPase mediated signal transduction (GO:0051056)	1.93
localization within membrane (GO:0051668)	1.84
protein localization to membrane (GO:0072657)	1.83
regulation of vesicle-mediated transport (GO:0060627)	1.69
intracellular protein transport (GO:0006886)	1.65
cytoskeleton organization (GO:0007010)	1.62
establishment of protein localization (GO:0045184)	1.59
protein transport (GO:0015031)	1.59
protein localization (GO:0008104)	1.56
cellular protein localization (GO:0034613)	1.48
cellular macromolecule localization (GO:0070727)	1.48
macromolecule localization (GO:0033036)	1.48
intracellular transport (GO:0046907)	1.46
establishment of localization in cell (GO:0051649)	1.43
nitrogen compound transport (GO:0071705)	1.43
organelle organization (GO:0006996)	1.42
cellular localization (GO:0051641)	1.39
organic substance transport (GO:0071702)	1.35
cellular component assembly (GO:0022607)	1.29
transport (GO:0006810)	1.28
establishment of localization (GO:0051234)	1.27
cellular component organization (GO:0016043)	1.26
regulation of signaling (GO:0023051)	1.25
cellular component organization or biogenesis (GO:0071840)	1.25
regulation of cell communication (GO:0010646)	1.24
localization (GO:0051179)	1.24
regulation of biological quality (GO:0065008)	1.24
cellular process (GO:0009987)	1.07
biological process (GO:0008150)	1.05
Unclassified (UNCLASSIFIED)	0.71
immune response (GO:0006955)	0.67
G protein-coupled receptor signaling pathway (GO:0007186)	0.5
adaptive immune response (GO:0002250)	0.4