Table 1.
Associated biosynthetic genes detected in R. intestinalis genome about essential amino acids or vitamins.
| Category | Name | KO | Gene | Biosynthesis protein |
|---|---|---|---|---|
| Essential amino acid | Tryptophan | ko: K01695 | trpA | tryptophan synthase alpha chain |
| ko: K01696 | trpB | tryptophan synthase beta chain | ||
| ko: K01867 | WARS | tryptophanyl-tRNA synthetase | ||
| methionine | ko: K00789 | metK | S-adenosylmethionine synthetase | |
| ko: K02071 | metN | D-methionine transport system ATP-binding protein | ||
| ko: K02072 | metI | D-methionine transport system permease protein | ||
| ko: K02073 | metQ | D-methionine transport system substrate-binding protein | ||
| threonine | ko: K01733 | thrC | threonine synthase | |
| ko: K01620 | ltaE | threonine aldolase | ||
| ko: K04720 | cobD | threonine-phosphate decarboxylase | ||
| Arginine | ko: K01585 | speA | arginine decarboxylase | |
| Cysteine | ko: K01738 | cysK | cysteine synthase | |
| ko: K04487 | iscS | cysteine desulfurase | ||
| Vitamins | Thiamine | ko: K00788 | thiE | thiamine-phosphate pyrophosphorylase |
| ko: K00949 | thiN | thiamine pyrophosphokinase | ||
| Riboflavin | ko: K00793 | ribE | riboflavin synthase | |
| Folate | ko: K11754 | folC | dihydrofolate synthase / folylpolyglutamate synthase | |
| ko: K00287 | DHFR | dihydrofolate reductase | ||
| Pantothenate | ko: K03525 | coaX | type III pantothenate kinase | |
| Biotin | ko: K01012 | bioB | biotin synthase |