Table 5.

Clinical chemistry results of 28-day repeated dose study.

	S0	S1	S2	S3	P
AST (U/L)	176.06 ± 57.97	229.68 ± 103.16	149.19 ± 23.92	145.71 ± 46.66	0.28
ALT (U/L)	42.06 ± 12.43	33.92 ± 4.48	36.4 ± 8.89	49.5 ± 11.26	0.17
DBIL (umol/L)	3.99 ± 0.75	5.11 ± 1.72	3.66 ± 0.39	3.91 ± 1.19	0.32
TBIL (umol/L)	11.02 ± 1.55	8.73 ± 1.01	8.35 ± 0.98	9.35 ± 1.45	0.05
ALP (U/L)	154.2 ± 19.17	140.39 ± 25.04	164.5 ± 29.73	140.22 ± 26.72	0.49
γGT (U/L)	1.92 ± 1.37	2.26 ± 0.83	2.62 ± 2.86	2.12 ± 0.5	0.94
TBA (umol/L)	4.73 ± 1.46	22.88 ± 36.04	6.38 ± 4.6	4.73 ± 3.31	0.45
UREA (umol/L)	26.4 ± 1.97	23.6 ± 3.19	25.07 ± 1.36	25.81 ± 2.64	0.42
CREA (umol/L)	26.83 ± 0.51	25.85 ± 1.75	23.98 ± 2.56	29.14 ± 6.19	0.26
UA (umol/L)	115.93 ± 36.31	107.9 ± 17.82	69.49 ± 13.33	69.66 ± 22.83	0.03