Table 1.
Univariate and multivariate analysis results for recurrence of HCC after LT in the training cohort.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| Model 1 | ||||
| Gender | 1.659 (0.716–3.842) | 0.237 | ||
| BMI | 0.916 (0.844–0.994) | 0.035 | 0.940 (0.839–1.052) | 0.283 |
| MELD score | 1.012 (0.972–1.053) | 0.570 | ||
| Log AFP LT | 1.517 (1.144–2.012) | 0.004 | 0.828 (0.487–1.408) | 0.828 |
| Endothelial angiopoietin-2*,** | 4.411 (2.352–8.272) | <0.001 | 5.634 (2.597–12.224) | <0.001 |
| Edmondson–Steiner grade* | 2.130 (1.460–3.106) | <0.001 | ||
| Microvascular invasion** | 3.246 (6.2920–11.904) | <0.001 | ||
| Milan Criteria | 1.886 (1.167–3.049) | 0.010 | 1.088 (0.505–2.347) | 0.829 |
| Metroticket Score | 0.998 (0.955–1.042) | 0.920 | ||
| Metroticket_AFP Score | 2.426 (1.387–4.244) | 0.002 | 1.724 (0.779–3.815) | 0.179 |
| AFP model | 1.279 (1.107–1.477) | <0.001 | 1.266 (0.963–1.665) | 0.092 |
| Number of downstaging treatments before LT | 1.091 (0.783–1.520) | 0.606 | ||
| Model 2 | ||||
| BMI | 0.916 (0.844–0.994) | 0.035 | 0.868 (0.782–0.963) | 0.004 |
| Edmondson–Steiner grade | 2.130 (1.460–3.106) | <0.001 | 1.341 (0.804–2.238) | 0.261 |
| Microvascular invasion | 3.246 (6.2920–11.904) | <0.001 | 3.676 (1.781–7.588) | <0.001 |
| Milan Criteria | 1.886 (1.167–3.049) | 0.010 | 1.154 (0.581–2.292) | 0.682 |
| Metroticket_AFP Score | 2.426 (1.387–4.244) | 0.002 | 1.360 (0.675–2.743) | 0.390 |
| AFP model | 1.279 (1.107–1.477) | <0.001 | 1.090 (0.845–1.405) | 0.508 |
*, **, collinear.