Table 4.
Univariate and multivariate analysis results for the survival of HCC after LT in the training cohort.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| Gender | 0.618 (0.267–1.434) | 0.263 | ||
| BMI | 0.947 (0.870–1.031) | 0.211 | ||
| MELD | 1.039 (1.000–1.079) | 0.048 | 1.044 (1.004–1.086) | 0.032 |
| Log AFP at transplant * | 1.574 (1.188–2.086) | 0.002 | ||
| Endothelial angiopoietin-2 *,**, *** | 2.622 (1.564–4.396) | 0.000 | 2.274 (1.232–4.999) | 0.009 |
| Edmondson–Steiner grade** | 1.651 (1.163–2.343) | 0.005 | ||
| Microvascular invasion *** | 2.987 (1.775–5.026) | 0.000 | ||
| Milan score | 0.698 (0.424–1.118) | 0.132 | ||
| Metroticket_AFP Score | 0.519 (0.299–0.901) | 0.020 | 0.533 (0.302–0.942) | 0.030 |
| AFP model^ | 1.440 (0.654–3.174) | 0.365 | ||
| Downstaging treatments before LT | 1.062 (0.768–1.467) | 0.717 | ||
*, **, *** collinear.
^ ref. Duvoux et al. (10).