Table 4.
Quality assessment of the experiments included in the studies.
| Study | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Zhang 2021 (7) | + | NR | NR | + | + | NR | + | + | NR | + | 6 |
| Dai 2021 (8) | + | NR | + | + | + | NR | + | + | + | + | 8 |
| Li 2020 (9) | + | NR | + | + | + | + | + | + | + | + | 9 |
| Wang 2019 (10) | + | NR | + | + | + | + | + | + | + | NR | 8 |
| Zheng 2021 (14) | + | NR | NR | + | + | NR | + | + | NR | + | 6 |
| Zheng 2020 (15) | + | NR | NR | + | + | NR | + | + | + | + | 7 |
| Zheng 2020 (16) | + | NR | NR | + | + | NR | + | + | + | + | 7 |
| Zhao 2020 (17) | + | NR | NR | + | + | NR | + | + | NR | + | 6 |
| Zhang 2020 (18) | + | NR | NR | + | + | NR | + | + | NR | + | 6 |
| Zhang 2020 (19) | + | NR | + | + | + | NR | + | + | NR | + | 7 |
| Zhang 2019 (20) | + | NR | NR | + | + | NR | + | + | NR | + | 6 |
| Yin 2019 (21) | + | NR | NR | + | + | NR | + | + | + | + | 7 |
| Yang 2020 (22) | + | NR | + | + | + | + | + | + | + | + | 9 |
| Xie 2021 (23) | + | NR | NR | + | + | NR | + | + | NR | + | 4 |
| Wang 2021 (24) | + | NR | + | + | + | – | + | + | + | + | 8 |
| Sun 2021 (25) | + | NR | + | + | + | NR | + | + | NR | + | 7 |
| Sun 2020 (26) | + | NR | + | + | + | + | + | + | + | + | 9 |
| Shi 2018 (27) | + | NR | NR | + | + | NR | + | + | NR | + | 6 |
| Li 2021 (28) | + | NR | NR | + | + | NR | + | + | + | + | 7 |
| Li 2019 (29) | + | NR | + | + | + | NR | + | NR | + | + | 7 |
| Li 2019 (30) | + | NR | + | NR | + | NR | + | + | NR | + | 6 |
| Li 2021 (31) | + | NR | NR | NR | + | NR | + | NR | NR | + | 4 |
| Li 2019 (32) | + | NR | NR | + | + | NR | + | + | + | + | 7 |
| Li 2021 (33) | + | NR | + | NR | + | + | + | + | NR | + | 7 |
| Hu 2019 (34) | + | NR | + | + | + | NR | + | NR | + | + | 7 |
| Dai 2021 (35) | + | NR | + | NR | + | NR | + | + | NR | + | 6 |
| Chen 2021 (36) | + | NR | + | NR | + | NR | + | + | NR | + | 6 |
| Jia 2021 (37) | + | NR | NR | + | + | NR | + | NR | + | NR | 5 |
| Qian 2021 (38) | + | NR | + | + | + | NR | + | + | + | NR | 7 |
| Guan 2021 (39) | + | NR | NR | NR | + | NR | + | + | NR | NR | 4 |
| Xia 2020 (40) | + | NR | + | + | + | NR | + | + | NR | NR | 6 |
| Xu 2020 (41) | + | NR | + | + | + | NR | + | NR | NR | NR | 5 |
| Zhu 2020 (42) | + | NR | + | + | + | NR | + | + | NR | NR | 6 |
| Yao 2020 (43) | + | NR | NR | NR | + | NR | + | + | NR | + | 4 |
| Wang 2019 (44) | + | NR | + | + | + | + | + | + | + | NR | 8 |
| Meng 2018 (45) | + | + | NR | + | + | + | + | + | NR | NR | 7 |
| Zheng 2021 (46) | + | NR | + | + | + | NR | + | + | + | NR | 7 |
| Huang 2020 (47) | + | NR | NR | NR | + | NR | + | + | NR | NR | 3 |
| Zhou 2020 (48) | + | NR | + | + | + | + | + | + | NR | NR | 7 |
| Yang 2017 (49) | + | NR | NR | + | + | + | + | NR | + | + | 7 |
| Feng 2019 (50) | + | + | + | + | + | NR | + | + | + | + | 9 |
| Zhao 2019 (51) | + | NR | + | NR | + | NR | + | + | NR | + | 6 |
1, peer-reviewed publication; 2, statements describing control of temperature; 3, randomization to treatment group; 4, allocation concealment; 5 blinded assessment of outcome; 6, avoidance of anesthetics with known notable intrinsic neuroprotective properties; 7, use of animals with relevant comorbidities; 8, sample size calculation; 9, compliance with animal welfare regulations; 10, declared any potential conflict of interest +: The article confirms the indicator and gets a point. -: This article does not meet this indicator and this indicator is not scored. NR: No description of the indicator in the article.