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. 2022 Sep 21;12(9):e061025. doi: 10.1136/bmjopen-2022-061025

Table 2.

Comparison of use of care and acute care management quality characteristics between the pre-wave, per-wave and post-wave periods

Global (N=6436) Pre-wave (N=4140) Per-wave (N=1080) Post-wave (N=1216) P value corrected (FDR)
n (%) n (%) n (%) n (%)
Use of care
 Calls to emergency services 6430 4135 1079 1216 0.083*
  No 2399 (37.3) 1590 (38.5) 372 (34.5) 437 (35.9)
  Yes 4031 (62.7) 2545 (61.5) 707 (65.5) 779 (64.1)
 Missing values 6 5 1 0
 FMC 6436 4140 1080 1216 0.332*
  EU 6278 (97.5) 4040 (97.6) 1059 (98.1) 1179 (9.0)
  MICU 158 (2.5) 100 (2.4) 21 (1.9) 37 (3.0)
 Symptoms-to-care time (min) 3157 1991 556 610 0.232†
  Median (IQR) 126 (38;401) 121 (38;384) 139 (46;488) 125 (38;392)
  Missing values 3279 2149 524 606
Acute care management quality
 EU admission-to-imaging time (min) 4819 3014 889 916 0.332†
  Median (IQR) 86 (47;194) 83 (45;201) 91 (51;175) 88 (52;191)
  Missing values 1617 1126 191 300
 Prehospital pathway type 6430 4135 1079 1216 0.040*
  Optimal pathway: calls to emergency services/MICU transport/EU 3719 (57.8) 2368 (57.3) 642 (59.5) 709 (58.3)
  Calls to emergency services/non-MICU transport/EU 312 (4.9) 177 (4.3) 65 (6.0) 70 (5.8)
  EU direct entry 2399 (37.3) 1590 (38.5) 372 (34.5) 437 (35.9)
  Missing values 6 5 1 0
 Mode of transport to the EU 6436 4140 1080 1216 0.812*
  Personal transport 732 (11.4) 475 (11.5) 117 (10.8) 140 (11.5)
  Non-MICU transport 4495 (69.8) 2902 (70.1) 758 (70.2) 835 (68.7)
  MICU transport 222 (3.4) 149 (3.6) 34 (3.1) 39 (3.2)
  Unknown 987 (15.3) 614 (14.8) 171 (15.8) 202 (16.6)
 Transfer to a stroke unit 6436 4140 1080 1216 0.923*
  No 752 (11.7) 484 (11.7) 123 (11.4) 145 (11.9)
  Yes 5684 (88.3) 3656 (88.3) 957 (88.6) 1071 (88.1)
 First imaging type 6041 3870 1019 1152 0.332‡
  MRI 3782 (62.6) 2395 (61.9) 650 (63.8) 737 (64.0)
  CT scan 2245 (37.2) 1463 (37.8) 369 (36.2) 413 (35.9)
  None 14 (0.2) 12 (0.3) 0 (0.0) 2 (0.2)
  Missing values 395 270 61 64
 IVT (all ischaemic strokes) 5660 3616 938 1106 0.011*
  No 4635 (81.9) 2913 (80.6) 801 (85.4) 921 (83.3)
  Yes 1025 (18.1) 703 (19.4) 137 (14.6) 185 (16.7)
  Missing values 9 1 3 5
  Exclusion 767 523 139 105
 IVT in ‘thrombolysis alert’ patients (ischaemic stroke) 1758 1100 310 348 0.011*
  No 1060 (60.3) 634 (57.6) 213 (68.7) 213 (61.2)
  Yes 698 (39.7) 466 (42.4) 97 (31.3) 135 (38.8)
  Missing values 2 1 0 1
  Exclusion 4676 3039 770 867
 Mechanical thrombectomy (all ischaemic stroke) 5620 3585 938 1097 0.332*
  No 4998 (88.9) 3170 (88.4) 842 (89.8) 986 (89.9)
  Yes 622 (11.1) 415 (11.6) 96 (10.2) 111 (10.1)
  Missing values 49 32 3 14
  Exclusion 767 523 139 105

Stroke cohort (N=6436).

2 test.

†Kruskal-Wallis test.

‡Fisher exact test.

CT, computerized tomography scan; EU, emergency unit; FDR, correction of p value by false discovery rate method; FMC, first medical contact; IVT, IV thrombolysis; MICU, mobile intensive care units; MRI, magnetic resonance imaging.