Table 3.
Iron and oxidative stress biochemistries at 28 weeks
| Biochemsitries | NL (n = 14) | CKD (n = 12) | CKD + IV iron (n = 13) | CKD + FC (n = 12) | ANOVA P-value |
|---|---|---|---|---|---|
| Hemoglobin (mg/dL) | 15.67 ± 0.58 | 13.00 ± 0.84a | 13.06 ± 0.53a | 13.08 ± 0.55a | 0.0002 |
| Hematocrit (%) | 52.08 ± 2.31 | 43.06 ± 1.27a | 43.45 ± 3.15a | 43.17 ± 2.32a | <0.0001 |
| Total iron (µg/dL) | 325.3 ± 45.32 | 287.5 ± 88.94 | 217.1 ± 57.85a | 266.7 ± 50.61 | 0.017 |
| UIBC (µg/dL) | 427.5 ± 35.85 | 325.3 ± 28.87a | 305.2 ± 53.22a | 202.6 ± 41.89a,b,c | <0.0001 |
| TIBC (µg/dL) | 752.8 ± 46.47 | 612.8 ± 76.75a | 499.7 ± 118.1a,b | 470.4 ± 83.58a,b | <0.0001 |
| TSAT (%) | 43.17 ± 4.49 | 46.08 ± 8.78 | 42.33 ± 4.12 | 56.00 ± 5.29a,b,c | <0.0001 |
| 8OHdG (ng/mL) | 18.59 ± 1.95 | 26.49 ± 3.68a | 26.61 ± 2.79a | 25.38 ± 2.22a | <0.0001 |
aTukey's post hoc different than NL rats, P < 0.05. bTukey's post hoc different than CKD, P < 0.05. cTukey's post hoc different than IV iron, P < 0.05.