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. 2022 Sep 22;12(41):26895–26907. doi: 10.1039/d2ra04015h

Inhibitory data of the target compounds against SARS-CoV-2 Mpro.

Compound's ID IC50 (µM ± SEa) Compound's ID IC50 (µM ± SE*)
17 329.5 ± 15.1 26 407.50 ± 3.44
21 25.36 ± 2.40 27 165.20 ± 16.70
22 236.50 ± 4.29 28 45.96 ± 8.62
23 65.92 ± 12.30 29 3.22 ± 2.83
24 82.17 ± 15.0 Lopinavir 82.17 ± 7.66
25 5.42 ± 21.30 GC-376 12.85 ± 0.74
a

SE represents standard deviation from triplicate readings.