Figure 2.

DMOG mimics transcriptional response to hypoxia and regulates the expression of genes involved in metabolism, cell cycle, and angiogenesis

Bubble charts for top 20 enriched Hallmark (A) and KEGG (B) pathways of upregulated (top) or downregulated DEGs (bottom) by DMOG. Heat maps of RNA-seq data showing significantly altered genes involved in glycolysis and TCA cycle (C), mitochondrial electron transport complex I and II (D), cell cycle (E), and angiogenesis (F). Each column corresponds to a sample and each row corresponds to a specific gene. KEGG, Kyoto Encyclopedia of Genes and Genomes. See also Figures S2 and S3.