Table 5. Sensitivity Analyses.
| Analysis | Week 16 vs baseline | Week 52 vs baseline | ||||
|---|---|---|---|---|---|---|
| No. | Mean (95% CI)a | P valueb | No. | Mean (95% CI)a | P valueb | |
| Primary analysis | 57 | −0.02 (−0.08 to 0.05) | .61 | 38 | −0.07 (−0.15 to 0.01) | .09 |
| Baseline TBR >1.6 | 25 | −0.12 (−0.24 to 0.01) | .07 | 16 | −0.21 (−0.35 to −0.08) | .005 |
| PASI score 75 | 20 | −0.09 (−0.24 to 0.05) | .18 | 12 | −0.14 (−0.30 to 0.02) | .07 |
| Treatment adherentc | 23 | −0.07 (−0.17 to 0.02) | .14 | 16 | −0.07 (−0.17 to 0.03) | .14 |
Abbreviations: PASI, Psoriasis Area and Severity Index; TBR, target to background ratio.
The 95% CI is for the difference between the later time vs the earlier time (paired t test).
From paired t test.
Defined as at least 90% adherent with all doses of apremilast.