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. 2022 Sep 21;158(12):1394–1403. doi: 10.1001/jamadermatol.2022.3862

Table 5. Sensitivity Analyses.

Analysis Week 16 vs baseline Week 52 vs baseline
No. Mean (95% CI)a P valueb No. Mean (95% CI)a P valueb
Primary analysis 57 −0.02 (−0.08 to 0.05) .61 38 −0.07 (−0.15 to 0.01) .09
Baseline TBR >1.6 25 −0.12 (−0.24 to 0.01) .07 16 −0.21 (−0.35 to −0.08) .005
PASI score 75 20 −0.09 (−0.24 to 0.05) .18 12 −0.14 (−0.30 to 0.02) .07
Treatment adherentc 23 −0.07 (−0.17 to 0.02) .14 16 −0.07 (−0.17 to 0.03) .14

Abbreviations: PASI, Psoriasis Area and Severity Index; TBR, target to background ratio.

a

The 95% CI is for the difference between the later time vs the earlier time (paired t test).

b

From paired t test.

c

Defined as at least 90% adherent with all doses of apremilast.