TABLE 4.
Summary of reported predictors of mortality for HIV-related CM for each study included in the narrative synthesis.
| Authors | Overall mortality predictors reported in a study | Reported predictors at 2 weeks | Reported predictors at 10 weeks |
| Luma et al. (37) | Male sex, younger 33.5 median, headache, neck stiffness, focal signs, cerebral edema on CT, Low CD4 | No data | No data |
| Patel et al. (4) | Low GCS, older > 50 years, aneamia, high WBC, low CSF WCC, renal dys, low sodium, | High WBC, low CSF WCC, No Amp B (induction) | ART hx, high sodium, No Amp B |
| Nussbaum et al. (46) | Flu monotherapy | Flu monotherapy | Flu monotherapy |
| Kizza et al. (47) | Diagnosis delay, lack of supportive care | No data | No data |
| Longley et al. (48) | Diagnosis delay, Low GCS | No data | No data |
| Lightowler et al. (49) | Focal neurological symptoms, DBP < 60, current TB, Flu monotherapy | Focal neurological symptoms, DBP < 60, current TB, Flu monotherapy | Focal neurological symptoms, DBP < 60, current TB, Flu monotherapy, missing CD4 |
| Gaskel et al. (50) | Fluconazole monotherapy | No data | No data |
| Hiesgen et al. (51) | ART naïve, ART default, N&V history | No data | No data |
| Bicanic et al. (52) | Low GCS, high fungal load, slow fungal clearance | No data | No data |
TB, tuberculosis; GCS, Glasgow coma scale; AmB, Amphotericin B; CT, computerized tomography scan; N&V, nausea and vomiting; ART, Antiretroviral therapy; DBP, diastolic blood pressure; WCC, CSF white cell count; WBC, white blood cells; No data- no data on predictors reported for the time point.