Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 8;13:974364. doi: 10.3389/fimmu.2022.974364

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Ghaemi, Roshani Asl, Zargaran, Ahmadi, Hashimi, Abdolalipour, Bathaeian and Miri

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Levels of Th1/Th2 cytokine balance secreted by splenocytes in immunized mice. The supernatants of splenocytes re-stimulated with RBD/N specific epitope, collected two and nine weeks after the last immunization. ELISA method was performed to determine the level of IFN-γ (A), IL-4 (B) and IL-12 (C) in splenocyte cultures. Results are representative of three independent experiments and are expressed as the mean ± SD. The RBD/N adjuvanted with Saponin induced strong levels of IFN-γ, IL-4 and IL-12 when compared to the other groups. **P < 0.01; ***P < 0.001. ns means nonstatistical difference.