TABLE 4.
Description of 7 Tesla high field MRI sequences proposed
| Sequence | Acquisition parameters | Measures assessed | Time (min) |
|---|---|---|---|
| Set up / localizer | GRE | Positioning; shimming | 5.5 |
| 3DT1 MP2RAGE | 348 slices (0.55 iso); TR∼6000; TE∼22.54; TI1/2∼800/2500; AF=2 | Morphometry; registration; hippocampus segmentation | 12.5 |
| 3D SWI | 208 slices (0.375x0.375x0.75); TR∼24; TE1/2∼8.16/18.35; AF=2 | Small vessel analysis; T2* mapping; QSM | 9 |
| T2 TSE | 36 slices (0.375x0.375x1.5); TR∼10060; TE∼61; AF = 2 | Hippocampus segmentation | 4 |
| T2 FLAIR | 80 slices (0.75x0.75x1.5); TR∼14000; TE∼99; TI∼2900; AF = 2 | White matter hyperintensities | 11 |
| 3D T2 Space | 256 slices (0.6 iso); TR∼3400; TE∼367; AF = 3 | Morphometry; hippocampus segmentation; perivascular spaces | 9.5 |
| MT & non MT | 60 slices (0.4 iso); TR=548; TE=4.08; AF = 8 | Locus coeruleus intensity; contrast' MT | 8 |
| TOF (4 slabs) | 192 slices (0.375 iso); TR∼14; TE∼4.5; AF = 3 | Angiography; arteriolar analysis | 6.5 |
Abbreviations: FLAIR, fluid‐attenuated inversion recovery; GRE, gradient echo; MT, magnetization transfer; MP2RAGE, magnetization‐prepared 2 rapid acquisition gradient echo; QSM, quantitative susceptibility mapping; SWI, susceptibility weighted imaging; TE, echo time; TOF, time of flight; TR, repetition time; TSE, turbo spin echo.