Table I.
Association between STX6 expression and clinical characteristics of patients with hepatocellular carcinoma.
| STX6 expression (IHC score) | ||||||
|---|---|---|---|---|---|---|
|
|
||||||
| Variables | No. (%) | Low (<6), n | High (≥6), n | Df | χ2 | P-value |
| Sex | 1 | 0.017 | 0.897 | |||
| Male | 76 (84.4) | 42 | 34 | |||
| Female | 14 (15.6) | 8 | 6 | |||
| Age, years | 1 | 0.057 | 0.810 | |||
| <55 | 37 (41.1) | 20 | 17 | |||
| ≥55 | 53 (58.9) | 30 | 23 | |||
| Size, cm | 1 | 9.085 | 0.003 | |||
| <5 | 56 (62.2) | 38 | 18 | |||
| ≥5 | 34 (37.8) | 12 | 22 | |||
| Diolame complete | 1 | 0.188 | ||||
| Yes | 54 | 31 | 23 | 0.665 | ||
| No | 36 | 19 | 17 | |||
| Number of tumors | 1 | 1.125 | 0.289 | |||
| Single | 72 (80) | 38 | 34 | |||
| Multiple | 18 (20) | 12 | 6 | |||
| TNM staging | 1 | 1.798 | 0.180 | |||
| I+II | 77 (85.6) | 45 | 32 | |||
| III+IV | 13 (14.4) | 5 | 8 | |||
| Microvascular invasion | 1 | 1.309 | 0.253 | |||
| No | 64 (71.1) | 38 | 26 | |||
| Yes | 26 (28.9) | 12 | 14 | |||
| Edmondson grade | 1 | 5.399 | 0.020 | |||
| I+II | 67 (74.4) | 42 | 25 | |||
| III | 23 (25.6) | 8 | 15 | |||
| Cirrhosis | 1 | 0.243 | 0.622 | |||
| Negative | 16 (17.8) | 8 | 8 | |||
| Positive | 74 (82.2) | 42 | 32 | |||
| HBV | 1 | 0.800 | 0.371 | |||
| Absent | 25 (27.8) | 12 | 13 | |||
| Present | 65 (72.2) | 38 | 27 | |||
| ALT, U/l | 1 | 0.458 | 0.499 | |||
| <45 | 55 (61.1) | 29 | 26 | |||
| ≥45 | 35 (38.9) | 21 | 14 | |||
| AFP, ng/ml | 1 | 5.478 | 0.019 | |||
| <400 | 69 (76.7) | 43 | 26 | |||
| ≥400 | 21 (23.3) | 7 | 14 | |||
AFP, α-fetoprotein; ALT, alanine aminotransferase; HBV, hepatitis B virus; IHC, immunohistochemistry; STX6, syntaxin 6.