Fig. 1.

PSO potential advantage for structure folding. The figure summarizes the PSO algorithm performance expectation on the 3D genome structure reconstruction problem. The figure shows two particles with their current local 3D structure representations using example 3D structures. In this illustration, Particle one has reached the best global minimum, however Particle two has a better upper half that is theoretically independent of the bottom half. The figure depicts the 3D structure that will be created once the PSO algorithm traverses particle two towards the structure in particle one in the next iteration