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. 2022 Sep 14;28(34):5023–5035. doi: 10.3748/wjg.v28.i34.5023

Table 5.

Risk factors associated with fetal negative outcomes

Clinical variables
Case/exposed 1
Crude OR (95%CI)
Adjusted OR (95%CI)
Head circumference ≤ 33 cm at birth
Maternal age, n (%)
< 35 118 /194 (60.8) 1 1
≥ 35 18 /194 (9.3) 1.1 (0.4-2.8); P = 0.82 2.0 (0.7-5.7); P = 0.19
Nulliparity, n (%)
No 53/194 (27.3) 1 1
Yes 83 /194 (42.8) 1.9 (1.0-3.6); P = 0.04 2.4 (1.2-4.9); P = 0.01
BMI, n (%)
< 30 120/194 (61.9) 1 1
≥ 30 16/194 (8.2) 0.4 (0.2-0.8); P = 0.008 0.3 (0.1-0.7); P = 0.003
HCV infection, n (%)
No 75/194 (38.7) 1 1
Yes 61/194 (31.4) 1.8 (0.9-3.5); P = 0.08 2.1 (1.1-4.3); P = 0.03
Intertuberous diameter, n (%)
≥ 8.5 85/194 (43.8) 1 1
< 8.5 51/194 (26.3) 1.1 (0.6-2.0); P = 0.86 1.0 (0.5-2.0); P = 0.75
Weight at birth ≤ 3250 gms
Age, n (%)
< 35 88/194 (45.4) 1 1
≥ 35 13/194 (6.7) 1.0 (0.4-2.3); P > 0.99 1.7 (0.6-4.3); P = 0.29
Nulliparity, n (%)
No 39/194 (20.1) 1 1
Yes 62/194 (32.0) 1.6 (0.9-2.8); P = 0.13 1.8 (0.9-3.4); P = 0.07
BMI, n (%)
< 30 88/194 (45.4) 1 1
≥ 30 13 /194 (6.7) 0.6 (0.3-1.2); P = 0.16 0.5 (0.2-1.1); P = 0.09
HCV infection HCV, n (%)
No 52/194 (26.8) 1 1
Yes 49/194 (25.3) 2.0 (1.1-3.5); P = 0.02 2.2 (1.2-4.0); P = 0.01
Intertuberous diameter, n (%)
≥ 8.5 61/194 (31.4) 1 1
< 8.5 40/194 (20.6) 1.2 (0.7-2.2); P = 0.46 1.1 (0.6-2.1); P = 0.66
1

Case/exposed: The case refers to the number of patients who presented with the specified variable and the Exposed refers to the total number of patients in the entire study cohort.

BMI: Body mass index; OR: Odds ratio.