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. 2022 Sep 3;11(9):1195. doi: 10.3390/antibiotics11091195

Table 1.

Comprehensive OLS regression of log10 microbial concentration depending on triclosan, material, strain and timeslot.

log(CFU) Coef. St.Err. t-Value p-Value 95% Conf Interval Sig.
S. epidermidis CIP 8155T 0 Reference level for microorganisms
C. albicans ATCC 10231 −0.097 0.124 −0.78 0.436 −0.339 0.147
C. albicans clinical −0.205 0.124 −1.66 0.098 −0.448 0.038
E. coli ATCC 25929 0.052 0.124 0.42 0.674 −0.191 0.295
E. coli ESBL clinical 0.183 0.124 1.48 0.140 −0.060 0.426
MRSA ATCC 33592 0.152 0.124 1.23 0.221 −0.195 0.395
MRSA clinical strain 0.048 0.124 0.38 0.700 −0.205 0.291
P. aeruginosa clinical 1.306 0.124 10.55 0.000 1.063 1.549 *
S. aureus ATCC 29213 0.170 0.124 1.37 0.170 −0.073 0.413
Polyglecaprone 25 0 Reference level for suture materials
Polyglactin 910 0.035 0.072 0.47 0.637 −0.105 0.175
Polydioxanone −0.015 0.072 −0.21 0.835 −0.156 0.125
No triclosan 0 Reference level for use of triclosan
Triclosan −2.256 0.058 −38.64 0.000 −2.370 −2.141 *
0 h 0 Reference level for hours
4 −0.379 0.083 −4.66 0.000 −0.541 −0.217 *
8 −0.237 0.083 −2.90 0.005 −0.399 −0.075 **
24 0.416 0.083 5.11 0.000 0.254 0.578 *
Overall model intercept 4.400 0.113 38.92 0.000 4.179 4.622 *
Number of obs 1296 Number of groups 324
F-test df = 141,281 p-value <0.0001
R-squared 0.5847 Adjusted R-squared 0.5802

* p < 0.001, ** p < 0.005, Sig.: significant, df: degrees of freedom, St. Err.: standard error. Hausman test: significance of: fails to meet the asymptotic assumptions. Breusch and Pagan Lagrangian multiplier test (LM) for random effects: p-value = 0.2085.