Table 2.
Phenotypic antimicrobial susceptibility testing via the broth microdilution method and genotypic characterization through whole-genome sequencing of K. pneumoniae Kpn1695.
| Parameter | Characterization |
|---|---|
| MLST 1 | 11 |
| K locus | KL 105 |
| O locus | O2V2 |
| IncFIB(K) | β-lactams (blaSCO-1, blaTEM-1, blaSHV-2), Aminoglycosides (aac(3)-IIa, aadA1) Sulfonamide (sul1) (Fluoro)quinolones (qnrE1) Tetracycline (tet(D)) |
| IncR | β-lactams (blaDHA-1, blaOXA-1) Aminoglycosides (aac(6′)-Ib-cr5, aph(3′)-Ia) Phenicols (catB3) Sulfonamide (sul1) Rifamycin (arr-3) * Quinolones (qnrB4) Macrolide (mph(A)) |
| ColRNAI | No antibiotic resistance genes found |
| Chromosome | Fosfomycin (fosA6) * Quinolones (GyrA-83L, ParC-80I) Polymyxins (arnT, eptAB, phoPQ) ** Macrolide (mdfA) Phenicol (oqxA, oqxB) |
| β-lactams (blaSHV-11) Outer membrane porins (OmpK37, OmpA) |
1 MLST = multi locus sequence typing, * no phenotypic data available to test for phenotypic rifamycin resistance, ** no phenotypic resistance was observed for colistin.