Compatibility matrix of nucleotide substitutions that were phylogenetically informative among the nine mtDNA haplotypes of C. albicans. X, incompatible (i.e., all four possible combinations of 2 nucleotides at the two variable positions are present in Fig. 1); –, compatible (i.e., fewer than all four possible combinations of 2 nucleotides at the two variable positions are present in Fig. 1). Region 2 was not included because none of the polymorphisms in this region was phylogenetically informative among the haplotypes. (The variation in region 2 only distinguishes haplotype 3 from all of the rest. Therefore, sites in region 2 cannot be incompatible with sites in other regions.)