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. 2022 Sep 8;13:962986. doi: 10.3389/fimmu.2022.962986

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Copyright © 2022 Shen, Teng, Wang, Guo, Xu, Huang, Xie, Zhou, Chen, Wang, Mao, Chen and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative pathology from FSGS patients before and after KTx by Periodic acid-Schiff staining. Note that focal segmental glomerular sclerosis with fibrosis is apparent in all FSGS patients before KTX and is also found in those with recurrent FSGS patients after KTx. Because KTx largely improved progressive renal injury in those FSGS patients, no renal biopsy was performed in the remission patients after KTx based on the ethical reasons. The healthy control kidneys are obtained from unmatched donor kidneys. Scale bar: 100um. KTx, kidney transplantation.