Figure 4.

Antibody-mediated humoral immunity against bacteriophage administration (mean ± SEM, n = 5). Second administration was performed 4 weeks after the first administration (indicated by the red arrow). Blue and orange bars represent native and polylactic-co-glycolic acid (PLGA)/alginate-encapsulated bacteriophage administered groups, respectively. Bars without and with stripes represent single (first)- or boost (second)-administered groups, respectively. Asterisk (*) indicates statistical significance.