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. 2022 Aug 30;11(9):1705. doi: 10.3390/antiox11091705

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Analysis of DEGs profiling of the liver in mice. (a) The DEGs between WT versus db/db groups and ICS II versus db/db groups were summarized in a Venn diagram. (b) The correlation coefficients between altered gene expression profiles were analyzed using hierarchical clustering analysis. (c) Top KEGG pathways enriched with DEGs and their matching P values. (d–f) Bar graph shows the fold enrichment values of the top 10 most significantly enriched terms for the regulation of genes, analyzed by GO terms.