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. 2022 Aug 30;11(9):1705. doi: 10.3390/antiox11091705

Figure 5.

Figure 5

Effect of ICS II on the protein expressions of PPARα, PPARβ, PPARγ, and NF-κB signaling pathway in the liver of db/db mice. Representative western blot and quantitation of PPARα (a), PPARβ (b), and PPARγ (c) protein expressions in the liver (n = 5). (d) Representative western blot of phosphorylation of IKKβ protein level and quantitation of phosphorylation of IKKβ protein level in the liver. (e) Representative western blot of IκB-α protein expression and quantitation of IκB-α protein expression in the liver. (f) Representative western blot of phosphorylation of NF-κB (p65) protein level and quantitation of phosphorylation of NF-κB (p65) protein level in the liver (n = 5). Serum inflammatory factors were measured, including TNF-α (g), IL-1β (h), and IL-6 (i) (n = 8). Data were expressed as mean ± SEM. ** p < 0.01 versus WT group; # p < 0.05 and ## p < 0.01 versus db/db group.