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Effects of compounds 1–5 and 1a on human hepatocellular carcinoma (HepG2) cell viability. HepG2 cells were treated with compounds 1 (A), 1a (B), 2 (C), 3 (D), 4 (E), and 5 (F) (6.2, 12.5, 25, 50, and 100 μM) for 24 h. The HepG2 cell viability was assessed using the Ez-Cytox cell viability assay. Cells were treated with culture media containing 0.5% DMSO as vehicle controls. Data are presented as the mean ± standard error of the mean (SEM). n = 3, * p < 0.05 compared with the control.
