Table 1.

The differentially expressed genes (DEGs) identified in Human Coronary Artery Endothelial Cells (HCAEC) and Human Internal Thoracic Endothelial Cells (HITAEC) exposed to mitomycin C (MMC) in comparison with the non-exposed control after applying the cut-off criterion (FDR p-value < 0.05, absolute fold change ≥ 2).

HCAEC	HITAEC
Upregulated genes
NECTIN4 (1175.6-fold), ENSG00000288684 (999.7-fold), SIGLEC14 (728.6-fold), ENSG00000285188 (697.5-fold), ENSG00000285245 (683.8-fold), ENSG00000144785 (654.5-fold), RBM14-RBM4 (647.1-fold), MUC19 (564.9-fold), ENSG00000287542 (542.6-fold), ATP5MF-PTCD1 (493.5-fold), ENSG00000261732 (467.4-fold), COL7A1 (431.6-fold), CD70 (384.7-fold), PAQR6 (361.5-fold), ENSG00000279686 (357-fold), ENSG00000258461 (353.4-fold), ST20-MTHFS (316.3-fold), GPR87 (307.7-fold), DENND2C (279-fold), GRHL3 (269.2-fold), UNC13A (215-fold), ENKUR (147.6-fold), IFIT2 (145.5-fold), GRIP2 (114-fold), B3GNT7 (95.6-fold), CDK18 (93.5-fold), TEDC2 (82.9-fold), BEX2 (61.2-fold), APOBEC3B (59.3-fold), CCL5 (18.8-fold), EPS8L2 (5.8-fold), PLTP (5.7-fold), SLC7A2 (5.1-fold), ATF3 (3.9-fold), CXCL8 (3.5-fold), VWCE (3.5-fold), GDF15 (3.3-fold), KLHL21 (3-fold), PIDD1 (2.9-fold), TYMS (2.8-fold), CX3CL1 (2.7-fold), E2F7 (2.7-fold), FDXR (2.7-fold), MDM2 (2.4-fold), PHLDA3 (2.4-fold), MMP10 (2.4-fold), SOD2 (2.3-fold), SELE (2.3-fold), BHLHE40 (2.3-fold), RUSC2 (2.2-fold), CDKN1A (2.2-fold), DCBLD2 (2.1-fold), AXL (2.1-fold), ATP13A3 (2.1-fold), MT2A (2.1-fold), TP53I3 (2-fold)	MDM2 (2.3-fold)
Downregulated genes
IQCJ-SCHIP1 (3-fold), LDB2 (2.2-fold), GIMAP8 (2.1-fold), BMX (2.1-fold), EFNB2 (2-fold), HMGCS1 (2-fold)	None detected