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. 2022 Sep 16;10(9):2306. doi: 10.3390/biomedicines10092306

Figure 1.

Figure 1

DPP4 in the adipose tissue. The red box shows the relationship between DPP4 and visceral adipose tissue inflammation, tissue remodeling, and dysfunction in humans. The blue box shows experimental data resulting from DPP4 ablation and pharmacological inhibition in rodents. Up arrows indicate an increase, down arrows a decrease. Abbreviations: DPP4: dipeptidyl peptidase 4, IL-6: interleukin 6, IL-12: interleukin 12, TNF-α: tumor necrosis factor α, AKT: protein kinase B; AT: adipose tissue. See Section 4.1 and Section 4.2 for detailed description and references.