Figure 5.

WBC and platelet membrane decoration to harness protein corona. (A) Based on the WBC membranes’ decoration, the biomimetic liposomes called leukosomes showed reduced nonspecific interactions and more adsorption of specific proteins over others, resulting in the ability to target inflamed endothelium and avoid clearance by macrophages [73]. Copyright 2017, American Chemical Society. (B) Poly(lactic-co-glycolic acid) (PLGA) NPs were decorated with the platelet membrane, showing reduced cellular uptake by macrophage cells and better therapeutic effects [75]. Copyright 2015, Springer Nature.