Figure 2.

Schematic representations of (A) vascularized adipose tissue and (B) paracrine interactions between both the vascular and adipose lineages. (C) Stepwise breakdown of cellular and paracrine activity during angiogenesis. Abbreviations: Platelet-derived growth factor-β (PDGF-β), transforming growth factor-β (TGF-β), vascular endothelial growth factor-A (VEGF-A), hepatocyte growth factor (HGF), angiopoietin-1,2 (Ang-1,2), fibroblast growth factor (FGF), insulin-like growth factor-1 (IGF-1), extracellular matrix (ECM), and matrix metalloproteinase (MMP). Created with Biorender.com.