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. 2022 Aug 5;11(16):e025058. doi: 10.1161/JAHA.121.025058

Figure 3. Survival curve of major adverse cardiovascular events (MACE)–free rate and insulin receptor substrate‐1 (IRS‐1), CYP2C19*2 genotypes.

Figure 3

Cox regression model adjusted for IRS‐1 or CYP2C19*2 genotypes and clinical covariates including age, previous myocardial infarction, hypertension, diabetes, smoking status, previous percutaneous coronary intervention, left ventricular ejection fraction, serum creatinine, low‐density lipoprotein, and diagnosis. A, Survival curve of MACE‐free rate and dominant model of IRS‐1 genotypes. B, Survival curve of MACE‐free rate and dominant model of CYP2C19*2 genotypes. C, Survival curve of MACE‐free rate and categorical model of IRS‐1 genotypes. D, Survival curve of MACE‐free rate and categorical model of CYP2C19*2 genotypes. HR indicates hazard ratio.