Table 3.

Cytoarchitectonic distribution of the TBI-induced cortical lesion in the EEG and MRI cohorts.

	EEG Cohort			MRI Cohort
Cortical Area	Area (mm2) (Mean ± SEM)	Min–Max	% of Rats	Area (Mean ± SEM)	Min–Max	% of Rats
DLEnt	0.27 ± 0.01	0.27–0.27	5 (2/43)			0 (0/30)
PRh	0.44 ± 0.11	0.01–1.35	44 (19/43)	0.79 ± 0.16	0.10–1.61	37 (11/30)
Ect	1.47 ± 0.20	0.01–3.82	77 (33/43)	1.77 ± 0.33	0.08–5.11	70 (21/30)
DI			0 (0/43)	0.18	0.18–0.18	3 (1/30)
GI			0 (0/43)	0.12 ± 0.05	0.03–0.24	13 (4/30) #
TeA	2.35 ± 0.17	0.01–3.92	91 (39/43)	2.33 ± 0.26	0.01–3.92	87 (26/30)
AuV	0.91 ± 0.09	0.01–2.45	93 (40/43)	1.22 ± 0.15	0.02–2.62	90 (27/30)
Au1	3.77 ± 0.20	0.86–5.78	100 (43/43)	4.32 ± 0.30 *	0.66–5.86	100 (30/30)
AuD	2.31 ± 0.06	0.58–2.61	100 (43/43)	2.32 ± 0.09	1.04–2.61	100 (30/30)
S1ULp	0.75 ± 0.09	0.03–1.98	93 (40/43)	1.14 ± 0.12 *	0.13–2.52	80 (24/30)
S1	1.16 ± 0.03	0.49–1.23	98 (42/43)	1.09 ± 0.05	0.02–1.23	97 (29/30)
S1BF	3.79 ± 0.36	0.56–10.44	98 (42/43)	3.42 ± 0.41	0.16–8.68	93 (28/30)
S1DZ	0.19 ± 0.06	0.02–0.3	9 (4/43)	0.01	0.01–0.01	3 (1/30)
PtPR	0.61 ± 0.03	0.06–0.75	95 (41/43)	0.61 ± 0.04	0.01–0.75	97 (29/30)
PtPD	0.47 ± 0.05	0.01–0.97	86 (37/43)	0.47 ± 0.05	0.01–0.96	83 (25/30)
V2L	4.62 ± 0.27	0.02–6.28	100 (43/43)	4.60 ± 0.32	0.87–6.48	100 (30/30)
V1B	2.12 ± 0.23	0.02–4.59	81 (35/43)	2.19 ± 0.30	0.15–4.81	80 (24/30)
V1	0.73 ± 0.16	0–2.13	56 (24/43)	0.37 ± 0.09	0.05–1.21	60 (18/30)
V1M	1.42 ± 0.26	0.01–3.98	47 (20/43)	1.32 ± 0.28	0.12–3.54	53 (16/30)
V2ML	0.68 ± 0.29	0.03–2.7	21 (9/43)	0.24 ± 0.14	0.01–0.76	17 (5/30)
V2MM	0.76 ± 0.50	0.04–2.26	9 (4/43)	0.28 ± 0.15	0.02–1.01	20 (6/30)
MPtA	0.04 ± 0.02	0.02–0.06	5 (2/43)			0 (0/30)
LPtA	0.83 ± 0.22	0.06–1.62	16 (7/43)	0.04 ± 0.03	0.01–0.09	10 (3/30)
S1Tr	0.54 ± 0.27	0.2–1.09	7 (3/43)			0 (0/30)
S1Sh	0.01	0.01–0.01	2 (1/43)			0 (0/30)
S1FL	0.12	0.12–0.12	2 (1/43)			0 (0/30)
S2	0.56 ± 0.07	0.04–2.10	95 (41/43)	1.07 ± 0.17 *	0.38–3.09	80 (24/30) #
RSD	1.09 ± 0.91	0.17–2.0	5 (2/43)	0.20 ± 0.08	0.02–0.42	13 (4/30)
RSGc	0.37	0.37–0.37	2 (1/43)			0 (0/30)
Sum of S1	4.89 ± 0.41	0.00–12.09	(43/43)	5.16 ± 0.55	0.00–11.55	(30/30)
Total S	5.43 ± 0.44	0.00–13.22	(43/43)	6.01 ± 0.65	0.00–12.59	(30/30)
Sum of V1	2.80 ± 0.46	0.00–10.20	(43/43)	2.68 ± 0.49	0.00–9.12	(30/30)
Sum of V2	4.84 ± 0.31	0.02–10.76	(43/43)	4.69 ± 0.34	0.87–7.71	(30/30)
Total V	7.63 ± 0.72	0.02–20.95	(43/43)	7.37 ± 0.78	0.87–15.82	(30/30)
Total Au	6.93 ± 0.34	1.44–10.84	(43/43)	7.73 ± 0.51	1.86–11.08	(30/30)
Total Area	25.33 ± 1.74	1.72–52.88	(43/43)	25.69 ± 2.32	5.66–47.61	(30/30)

Abbreviations: Au1, primary auditory cortex; AuD, secondary auditory cortex, dorsal area; AuV, secondary auditory cortex, ventral area; DLEnt, dorsolateral entorhinal cortex; DI, dysgranular insular cortex; Ect, ectorhinal cortex; GI, granular insular cortex; LPtA, lateral parietal association cortex; MPtA, medial parietal association cortex; PRh, perirhinal cortex; PtPD, parietal cortex, posterior area, dorsal part; PtPR, parietal cortex; RSD, retrosplenial dysgranular cortex; RSGc, retrosplenial granular cortex, c region; S1, primary somatosensory cortex; S2, secondary somatosensory cortex; S1BF, primary somatosensory cortex, barrel field; S1DZ, primary somatosensory cortex, dysgranular zone; S1FL, primary somatosensory cortex, forelimb region; S1Sh, primary somatosensory cortex, shoulder region; S1Tr, primary somatosensory cortex, trunk region; S1ULp, primary somatosensory cortex, upper lip region; TeA, temporal association cortex; V1, primary visual cortex; V1M, primary visual cortex, monocular area; V1B, primary visual cortex, binocular area; V2L, secondary visual cortex, lateral area; V2ML secondary visual cortex, mediolateral area; V2MM, secondary visual cortex, mediomedial area. Area is shown as a mean ± standard error of the mean (SEM). Animal numbers are in parenthesis. Statistical significances: *, p < 0.05 as compared to the area in the EEG cohort (Mann-Whitney U); ^#, p < 0.05 as compared to the percentage of rats in the EEG cohort (ꭕ² test).