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. 2022 Sep 2;10(9):2168. doi: 10.3390/biomedicines10092168

Figure 4.

Figure 4

Selective binding of mAbs to pathogenic species of α-syn by SPR. The binding response of immobilized mAbs to α-syn monomers, toxic oligomers, soluble (sonicated) PFFs and physiologic (Phys.) tetramers was measured by SPR. An antibody reactive with all species of α-syn (Pan α-syn) was used as a positive control. The same pattern of binding was observed in 4 independent experiments.