Figure 5. Notable gut bacteria that are associated with vulnerable features and inflammatory/prothrombotic blood biomarkers.

Dysgonomonas (associated with the presence of TCFA) had a significant positive correlation with IL‐6, Paraprevotella (associated with the presence of TCFA, decrease in FCT, and increase in PAV) had a significant positive correlation with fibrinogen and negative correlation with HDL‐C, Succinatimonas (associated with a decrease in FCT and increase in PAV) had significant positive correlations with fibrinogen and homocysteine, and Bacillus (associated with a decrease in FCT and increase in TAV_normalized) had significant positive correlations with fibrinogen and hs‐CRP. Anaerostipes (associated with an increase in FCT and decrease in lipid index, PAV, and TAV_normalized) had significant negative correlations with TMAO, TNFα, and IL‐6, and Dielma (associated with an increase in FCT) had negative correlations with white blood cells, TMAO, PAI‐1, and homocysteine and a positive correlation with HDL‐C. FCT indicates fibrous cap thickness; HDL‐C, high‐density lipoprotein cholesterol; hs‐CRP, high‐sensitivity C‐reactive protein; IL, interleukin; PAI‐1, plasminogen activator inhibitor‐1; PAV, percent atheroma volume; TAV_normalized, normalized total atheroma volume; TCFA, thin‐cap fibroatheroma; TMAO, trimethylamine N‐oxide; TNFα, tumor necrosis factor α; and WBC, white blood cell.