Table 1.
Baseline and Procedural Characteristics
| No drop | Minimal drop (<3 g/dL) | Minor drop (≥3 and<5 g/dL) | Major drop (≥5 g/dL) | P value | |
|---|---|---|---|---|---|
| n=35 (2.9%) | n=894 (74.3%) | n=214 (17.8%) | n=61 (5.1%) | ||
| Hemoglobin on admission, mean (SD), g/dL | 12.2 (2.4) | 14.3 (1.5) | 14.7 (1.5) | 14.9 (1.5) | <0.001 |
| Nadir hemoglobin, mean (SD), g/dL | 12.2 (2.4) | 12.7 (1.6) | 11.0 (1.6) | 8.9 (1.6) | <0.001 |
| Age, mean (SD), y | 62.4 (10.6) | 61.3 (13.0) | 65.5 (12.7) | 65.4 (13.4) | <0.001 |
| Men, n (%) | 28 (80.0) | 701 (78.4) | 153 (71.5) | 36 (59.0) | 0.002 |
| Diabetes, n (%) | 4 (11.4) | 158 (17.7) | 47 (22.0) | 20 (32.8) | 0.011 |
| BMI, mean (SD), kg/m2 | 25.9 (3.3) | 26.8 (4.0) | 26.6 (3.9) | 26.2 (3.1) | 0.359 |
| Hypercholesterolemia, n (%) | 28 (80.0) | 485 (54.3) | 101 (47.2) | 35 (57.4) | 0.003 |
| Hypertension, n (%) | 24 (68.6) | 617 (69.0) | 153 (71.5) | 52 (85.2) | 0.060 |
| Current smoking, n (%) | 10 (28.6) | 391 (43.7) | 88 (41.1) | 27 (44.3) | 0.319 |
| Family history for cardiovascular disease, n (%) | 9 (25.7) | 370 (41.4) | 86 (40.2) | 15 (24.6) | 0.009 |
|
CrCL mean (SD), mL/min |
83.2 (30.5) | 90.0 (33.4) | 81.8 (36.9) | 75.3 (29.1) | <0.001 |
| No. of affected vessels (%) | 0.007 | ||||
| 1 | 11 (31.4) | 342 (38.3) | 62 (29.0) | 12 (19.7) | |
| 2 | 10 (28.6) | 279 (31.2) | 65 (30.4) | 22 (36.1) | |
| 3 | 14 (40.0) | 273 (30.5) | 87 (40.7) | 27 (44.3) | |
| Previous MI, n (%) | 13 (37.1) | 115 (12.9) | 15 (7.0) | 8 (13.1) | <0.001 |
| Previous CABG, n (%) | 2 (5.7) | 22 (2.5) | 11 (5.1) | 3 (4.9) | 0.136 |
| Time to admission, mean (SD), h | 5.0 (5.28) | 6.8 (6.1) | 6.3 (5.7) | 6.6 (6.1) | 0.242 |
| Door‐to‐balloon time, mean (SD), h | 1.4 (0.7) | 1.5 (0.9) | 1.3 (0.7) | 1.3 (0.8) | 0.010 |
| Killip class, n (%) | <0.001 | ||||
| I | 22 (62.9) | 698 (78.1) | 137 (64.0) | 36 (59.0) | |
| II | 9 (25.7) | 162 (18.1) | 49 (22.9) | 13 (21.3) | |
| III | 3 (8.6) | 18 (2.0) | 17 (7.9) | 1 (1.6) | |
| IV | 1 (2.9) | 16 (1.8) | 11 (5.1) | 11 (18.0) | |
| Baseline TIMI flow, n (%) | 0.630 | ||||
| 0 | 12 (34.4) | 411 (46.0) | 112 (52.6) | 31 (50.8) | |
| 1 | 3 (8.6) | 99 (11.1) | 27 (12.7) | 7 (11.5) | |
| 2 | 11 (31.4) | 209 (23.4) | 45 (21.1) | 13 (21.3) | |
| 3 | 9 (25.7) | 174 (19.5) | 29 (13.6) | 10 (16.4) | |
| Type of PCI, n (%) | 0.277 | ||||
| PTCA, n (%) | 5 (14.3) | 128 (14.3) | 22 (10.3) | 7 (11.5) | |
| Stenting, n (%) | 30 (85.7) | 766 (85.7) | 192 (89.7) | 54 (88.5) | |
| No reflow, n (%) | 5 (14.3) | 98 (11.0) | 46 (21.6) | 16 (26.2) | <0.001 |
| LVEF, mean (SD), % | 47.7 (13.0) | 49.8 (11.0) | 47.0 (12.3) | 45.5 (13.1) | <0.001 |
| Infarct vessel (culprit lesion), n (%) | 0.875 | ||||
| Left main | 0 (0) | 4 (0.5) | 0 (0) | 0 (0) | |
| LAD | 20 (57.1) | 400 (44.7) | 97 (45.3) | 22 (36.1) | |
| LCX | 3 (8.6) | 153 (17.1) | 34 (15.9) | 12 (19.7) | |
| RCA | 11 (31.4) | 322 (36.0) | 79 (36.9) | 26 (42.6) | |
| CABG surgery | 1 (2.9) | 15 (1.7) | 4 (1.9) | 1 (1.6) |
BMI indicates body mass index; CABG, coronary artery bypass graft; CrCl, creatinine clearance; LAD, left anterior descending coronary artery; LCX, left circumflex coronary artery; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PCI, percutaneous coronary intervention; PTCA, percutaneous transluminal coronary angioplasty; RCA, right coronary artery; and TIMI, thrombolysis in myocardial infarction.