Table 2.
Patient demographics for low and high differential MYC expression.
| Parameter | Low MYC Expression |
High MYC Expression |
p-Value |
|---|---|---|---|
| Patients, n | 8 | 13 | |
| Age at Diagnosis, median (IQR) | 40 (39–44) | 47 (46–48) | 0.043 |
| Sex | 0.37 | ||
| Male, n (%) | 6 (75%) | 6 (46%) | |
| Female, n (%) | 2 (25%) | 7 (54%) | |
| Race | 0.13 | ||
| White, n (%) | 6 (75%) | 13 (100%) | |
| Black, n (%) | 1 (13%) | 0 (0%) | |
| Asian, n (%) | 1 (13%) | 0 (0%) | |
| BMI | 0.047 | ||
| Normal or underweight, n (%) | 4 (50%) | 1 (8%) | |
| Overweight or Obese, n (%) | 4 (50%) | 12 (92%) | |
| History of Smoking a, n (%) | 4 (50%) | 4 (31%) | 0.65 |
| Family History b, n (%) | 1 (13%) | 8 (62%) | 0.067 |
| Located at Sigmoid or Rectum, n (%) | 3 (38%) | 11 (85%) | 0.056 |
| Overall Stage | 0.53 | ||
| I, n (%) | 1 (13%) | 5 (38%) | |
| II, n (%) | 2 (25%) | 1 (8%) | |
| III, n (%) | 4 (50%) | 6 (46%) | |
| IV, n (%) | 1 (13%) | 1 (8%) | |
| Signet/Mucinous component | 4 (50%) | 0 (0%) | 0.012 |
| Lymphovascular Invasion | 3 (38%) | 4 (31%) | 1.00 |
| Peri-neural Invasion | 3 (38%) | 3 (23%) | 0.63 |
a Positive smoking status includes both current and former smokers at the time of surgery; b Positive family history for colon or rectal cancer in first degree family member. Bold values represent statistically significant differences between high-MYC and low-MYC groups (Fisher’s exact test, p < 0.05).