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. 2022 Aug 23;12(9):1117. doi: 10.3390/brainsci12091117

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Immature Neuronal Population Inspection of DCX-positive neurons in the dentate gyrus indicates a visibly lower population in FAE (A,B) versus control (C,D) subjects. There was a significant reduction of DCX-positive neurons in the dentate gyrus of FAE subjects as compared to controls. The population of DCX-positive neurons was negatively correlated with daily ethanol exposure and average BEC, but not with total exposure. Control values are shown for each correlation graph for illustration purposes only as they were not incorporated in the correlational analysis. * p < 0.05 FAE vs. control. (A,C) scale bar = 100 µm; (B,D) (inset box) scale bar = 10 µm.