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. 2022 Sep 10;14(18):4407. doi: 10.3390/cancers14184407

Table 4.

Correlation between microbial DNA fragments, Toll-like receptor (TLR) and vitamin D receptor (VDR) polymorphisms parameters (values against each category represents p-values).

Target TLR VDR
Gene Target TLR2-196 to -174bp TLR4—D299G TLR4—T399I TLR9—T1237C TLR9—T1486C TaqI ApaI FokI BsmI
16S rRNA 0.172 0.009 0.043 0.549 0.567 <0.001 0.112 <0.001 0.2534
Escherichia coli 0.074 0.091 0.093 0.617 0.548 <0.001 0.003 0.0590 0.553
Bacteroides fragilis 0.522 0.025 0.087 0.229 0.258 <0.001 0.009 <0.001 0.075
Candida albicans 0.528 0.798 0.619 0.896 0.928 <0.001 0.015 0.027 0.029
TLR2-196 to -174bp <0.001 <0.001 <0.001 <0.001 0.671 0.399 0.080 0.004
TLR4—D299G <0.001 <0.001 <0.001 <0.001 0.043 <0.001 0.015 <0.001
TLR4—T399I <0.001 <0.001 <0.001 <0.001 0.042 <0.001 0.036 <0.001
TLR9—T1237C <0.001 <0.001 <0.001 <0.001 0.364 0.008 0.012 <0.001
TLR9—T1486C <0.001 <0.001 <0.001 <0.001 0.423 0.018 0.029 <0.001
TaqI 0.671 0.043 0.042 0.364 0.423 0.395 <0.001 <0.001
ApaI 0.399 <0.001 <0.001 0.008 0.018 0.395 <0.001 <0.001
FokI 0.080 0.015 0.036 0.012 0.027 <0.001 <0.001 <0.001
BsmI 0.003 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001