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. 2022 Sep 18;14(18):4519. doi: 10.3390/cancers14184519

Table 2.

Outcome of TP53-mutated myeloid malignancy patients treated with hypomethymating agents. CR: Complete Remission, EFS: Event Free Survival, OS: Overall Survival.

Regimen Demographics CR EFS OS References
Azacitidine 20–91 y/o 20–40% Not available Median OS: 7 months [34,35,36,41]
Decitabine 47–90 y/o 30% Median EFS: 6 months Median OS: 2.1–7 months [28,35,37,38,39,40]