Table 4.
Univariate analysis of predicting factors of overall and recurrence-free survivals and severe postoperative complications in completely resected patients.
| Overall Survival | Recurrence-Free Survival | Severe Complications | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | HR | 95% CI | p | HR | 95% CI | p | OR | 95% CI | p | |
| Age, ≥60 yo | 108 | 0.55 | 0.11, 2.83 | 0.5 | 0.99 | 0.46, 2.16 | >0.9 | 1.43 | 0.67, 3.09 | 0.4 |
| Sex, Male | 108 | 2.84 | 0.63, 12.8 | 0.2 | 0.91 | 0.40, 2.10 | 0.8 | 0.95 | 0.43, 2.10 | >0.9 |
| CEA, >15 IU | 83 | 4.28 | 0.94, 19.4 | 0.059 | 2.50 | 0.94, 6.61 | 0.065 | 1.14 | 0.41, 3.30 | 0.8 |
| CA-19.9, >20 IU | 80 | 2.04 | 0.41, 10.1 | 0.4 | 1.67 | 0.62, 4.49 | 0.3 | 0.72 | 0.29, 1.80 | 0.5 |
| CA-125, >41 IU | 66 | 6.47 | 1.23, 34.1 | 0.028 | 3.17 | 1.08, 9.32 | 0.036 | 1.32 | 0.49, 3.59 | 0.6 |
| Histologic grade, high | 84 | 2.31 | 0.32, 16.5 | 0.4 | 4.20 | 1.74, 10.2 | 0.001 | 2.06 | 0.72, 6.22 | 0.2 |
| PCI, >25 | 108 | 7.00 | 1.51, 32.5 | 0.013 | 1.37 | 0.47, 4.01 | 0.6 | 1.43 | 0.52, 4.06 | 0.5 |
| Scalloping | 108 | |||||||||
| none | - | - | - | - | - | - | ||||
| hepatic | 0.00 | 0.00, Inf | >0.9 | 0.78 | 0.23, 2.68 | 0.7 | 0.30 | 0.06, 1.06 | 0.083 | |
| hepatic + splenic | 1.78 | 0.40, 7.94 | 0.5 | 0.88 | 0.35, 2.23 | 0.8 | 1.79 | 0.74, 4.49 | 0.2 | |
| Liver scalloping | ||||||||||
| max depth, >15 mm | 43 | 1.19 | 0.11, 13.1 | 0.9 | 1.12 | 0.28, 4.49 | 0.9 | 1.64 | 0.46, 6.17 | 0.5 |
| max depth Hotta, >20 mm | 43 | 1.33 | 0.12, 14.9 | 0.8 | 1.24 | 0.31, 4.99 | 0.8 | 1.64 | 0.46, 6.17 | 0.5 |
| max length, >60 mm | 43 | 4.28 | 0.39, 47.3 | 0.2 | 1.32 | 0.33, 5.28 | 0.7 | 1.33 | 0.36, 5.07 | 0.7 |
| ratio max depth/length, >0.4 | 43 | 0.00 | 0.00, Inf | >0.9 | 0.48 | 0.06, 3.88 | 0.5 | 2.53 | 0.57, 13.6 | 0.2 |
| Splenic scalloping | ||||||||||
| max depth, >8 mm | 29 | 0.21 | 0.02, 2.37 | 0.2 | 0.43 | 0.09, 2.13 | 0.3 | 0.16 | 0.01, 1.11 | 0.11 |
| max depth Hotta, >20 mm | 29 | 0.00 | 0.00, Inf | >0.9 | 0.56 | 0.06, 4.79 | 0.6 | 0.34 | 0.06, 1.72 | 0.2 |
| max length, >40 mm | 29 | 3.62 | 0.33, 40.3 | 0.3 | 0.96 | 0.17, 5.25 | >0.9 | 0.32 | 0.06, 1.51 | 0.2 |
| ratio max depth/length, >0.4 | 29 | 0.00 | 0.00, Inf | >0.9 | 0.00 | 0.00, Inf | >0.9 | 1.29 | 0.20, 10.7 | 0.8 |
| ROI density (HU) | ||||||||||
| ratio ROI scal/aorta ≥ 0.3 | 43 | 1.37 | 0.12, 15.2 | 0.8 | 1.52 | 0.38, 6.11 | 0.6 | 4.00 | 0.79, 30.0 | 0.12 |
| ratio ROI scal/healthy liver ≥ 0.6 | 43 | 2.95 | 0.26, 32.9 | 0.4 | 1.37 | 0.36, 5.12 | 0.6 | 3.37 | 0.88, 14.9 | 0.085 |
yo, years old; HR, hazard ratio; CI, confidence interval; OR, odds ratio; PCI, peritoneal carcinomatosis index; scal, scalloping; ROI, region of interest; Inf, inferior to 0.