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. 2022 Sep 8;14(18):4377. doi: 10.3390/cancers14184377

Table 1.

Detailed overview of the studies reporting CDH1 gene methylation in lobular breast cancer. Only publications analyzing more than 10 cases of lobular breast cancer are included.

Study n = Methylated Cases Method Reference
Droufakou et al.
Int. J. Cancer 2001
22 17 (77%) MSP [75]
Sarrio et al.
Int. J. Cancer
46 19 (41%) MSP [89]
Lombaerts et al.
BBRC
11 8 (73%) MSP [90]
Shinozaki et al.
Clin. Cancer Res. 2005
33 12 (36%) MSP [73]
Zou et al.
J. Pathol. 2009
14 13 (93%) MSP [91]
Ciriello et al.
Cell 2015
127 0 450 k array + NGS [92]
Liu et al.
Oncol. Lett. 2016
31 8 (26%) MSP [81]
Alexander et al.
Cancers 2022
18 0 EPIC array [93]