Figure 2.
The effect of the AMPK inhibitor dorsomorphin on migration and adhesion in human bladder cancer cells after FXR overexpression. (A) The migratory ability of FXR-overexpressing (FXR-O) TSGH8301 and T24 cells treated with or without dorsomorphin (5 μM) was analyzed by wound healing assay after scratching for 6 h. The right panel shows the relative migration rate. (B) The adhesive ability in FXR-O TSGH8301 and T24 cells treated with or without dorsomorphin was analyzed after 50 min of incubation. Then, the adherent cells were stained and photographed. The right panel shows the relative numbers of adherent cells. ** p < 0.01 compared to the control group. # p < 0.05; ## p < 0.01 compared to the FXR-O group. Scale bar = 200 μm.