Table 3.
Menstrual history of the patients and serum chromosomal analysis of both premature ovarian insufficiency and Turner syndrome groups in the sequencing cohort.
| Menarche (Age) | Duration of Amenorrhea (Months) |
Karyotype | FMR Gene Mutation |
|
|---|---|---|---|---|
| POI | ||||
| 1 | 15 | 18 | 46,XX | Normal |
| 2 | 13 | 24 | 47,XXX [39]/46,XX[1] | Normal |
| 3 | 15 | 24 | 46,XX | Normal |
| 4 | 16 | 36 | 46,XX | Normal |
| 5 | 12 | 3 | 46,XX | Normal |
| 6 | 15 | 5 | 46,XX | Normal |
| 7 | 14 | 30 | 46,XX | Normal |
| Turner Syndrome | ||||
| 1 | no menarche | NA | 46,X,i(X)(q10),22pstk+[16]/45,X,22pstk+[14] | Normal |
| 2 | no menarche | NA | 46,X,i(X)(q10) | Normal |
| 3 | no menarche | NA | 45,X | Normal |
| 4 | no menarche | NA | 46,X,i(X)(q10) | Normal |
| 5 | no menarche | NA | 46,X,i(X)(q10)[24]/45,X[6] | Normal |
| 6 | no menarche | NA | 45,X | Normal |
| 7 | no menarche | NA | 45,X | Normal |
Abbreviations: FMR, fragile X mental retardation 1; NA, not available; POI, premature ovarian insufficiency.