Table 4.

Menstrual history of the patients and serum chromosomal analysis of both premature ovarian insufficiency and Turner syndrome groups in the validation cohort.

	Menarche (Age)	Duration of Amenorrhea (Months)	Karyotype	FMR Gene Mutation
POI
1	no menarche	NA	46,XX	Normal
2	15	18	46,XX	Normal
3	1516	10	46,XX	Normal
4	1414	6	46,XX	Normal
5	1216	70	46,XX	Normal
6	1215	6	46,XX,16qh+	Normal
7	11	120	46,XX	Normal
8	13	24	47,XXX[39]/46,XX[1]	Normal
9	14	120	46,XX,1qh+	Normal
10	15	24	46,XX	Normal
11	13	12	46,XX	Normal
12	14	24	46,XX	Normal
13	12	36	46,XX	Normal
14	no menarche	NA	46,XX	Normal
15	14	22	46,XX	Normal
Turner Syndrome
1	no menarche	NA	45,X	Normal
2	no menarche	NA	46,X,i(X)(q10)	Normal
3	no menarche	NA	46,X,i(X)(q10)[24]/45,X[6]	Normal
4	no menarche	NA	45,X	Normal
5	no menarche	NA	45,X[21]/46,X,idic(X)(q25)[9]	Normal
6	no menarche	NA	46,X,i(X)(q10)	Normal
7	no menarche	NA	45,X	Normal
8	no menarche	NA	45,X[17]/46,X,i(X)(q10)[13]	Normal
9	no menarche	NA	46,X,i(X)(q10),22pstk+[16]/45,X,22pstk+[14]	Normal
10	no menarche	NA	45,X/46,XX	Normal
11	no menarche	NA	46,X,idic(X)(q22.1)[28]/45,X[22]	Normal

Abbreviations: FMR, fragile X mental retardation 1; NA, not available; POI, premature ovarian insufficiency.