Table 5.
Univariate and multivariate analyses of clinicopathological factors and risk stratification markers expression for overall survival.
| Factors | Number of Patients |
Univariate | p-Value | Multivariate | p-Value | |||
|---|---|---|---|---|---|---|---|---|
| HR | 95%CI | HR | 95%CI | |||||
| Age | ≦65 | 217 | 1 | 1 | ||||
| >65 | 230 | 1.42 | 1.08–1.88 | 0.014 | 1.38 | 1.04–1.83 | 0.025 | |
| Sex | female | 134 | 1 | |||||
| male | 313 | 1.12 | 0.82–1.51 | 0.482 | ||||
| Histological type | well/moderately/ | 193 | 1 | |||||
| poorly | 254 | 1.07 | 0.81–1.41 | 0.643 | ||||
| Lymphatic invasion | (−) | 132 | 1 | |||||
| (+) | 315 | 0.96 | 0.71–1.29 | 0.780 | ||||
| Venous invasion | (−) | 128 | 1 | |||||
| (+) | 319 | 1.26 | 0.93–1.71 | 0.138 | ||||
| Stage | II | 170 | 1 | 1 | ||||
| III | 277 | 1.46 | 1.10–1.94 | 0.009 | 1.47 | 1.11–1.96 | 0.008 | |
| Combination of survival stratification markers * | 0–1 | 394 | 1 | 1 | ||||
| 2–4 | 53 | 1.82 | 1.21–2.72 | 0.004 | 1.71 | 1.14–2.56 | 0.010 | |
Well = well-differentiated adenocarcinoma; moderately = moderately differentiated adenocarcinoma; poorly = poorly differentiated adenocarcinoma; * = PDGFRB, MMP11, INHBA, and galectin-10.