Figure 3.

circ_0059707 inhibited the growth of leukemia cells in vitro and in vivo. (A) circ_0059707 relative expression, as detected by qRT-PCR. (B) The effect of circ_0059707 expression on cell growth. (C) The effect of circ_0059707 expression on cellular apoptosis, as detected by flow cytometry. (D) Body weight curve for nude mice. (E) Tumor volume curve for nude mice. (F) Weight of subcutaneous tumors from nude mice. (G) Relative expression of levels of circ_0059707 in the tumor tissue, as detected by qRT-PCR. (H) HE staining of tumor tissue (200×). (I) Red blood cell count in the peripheral blood. **, compared with the NC group, p < 0.01.