Table 9.

Results of the inter-observer variability test using MSF MIC panels with the Prompt inoculation method versus the standard AST method.

	Staphylococci and Enterococci				Gram-negative bacilli				Fastidious organisms
Antimicrobial	n a	Kappa Cohen	R1 CA b [%]	R2 CA c [%]	n a	Kappa Cohen	R1 CA b [%]	R2 CA c [%]	n a	Kappa Cohen	R1 CA b [%]	R2 CA c [%]
Penicillin	63	0.95	98	98					87	0.99	97	97
Ampicillin	123	0.76	96	92	112	0.91	99	98	107	1.00	98	98
Amoxicillin/Clavulanic Ac					112	0.97	99	98
Cefoxitin screening/Oxacillin	74	0.95	92	93
Ceftazidime					127	0.95	97	96
Ceftriaxone					112	0.89	97	98	20	1.00	100	100
ESBL test					112	0.97	99	97
Piperacillin/Tazobactam					127	0.97	99	93
Levofloxacin									83	0.98	100	100
Ciprofloxacin	49	0.89	99	99	141	0.95	94	96
Amikacin	123	0.78	78	76	141	0.99	99	93
Gentamicin	123	0.92	100	96	141	1.00	92	92
Gentamicin (high level)	49	0.90	90	90
Teicoplanin	123	0.79	99	96
Vancomycin	123	1.00	97	97					87	1.00	98	98
Quinupristin-dalfopristin	123	0.93	89	91
Erythromycin	74	0.97	96	96
Clindamycin	74	0.99	97	97					87	0.64	100	100
Inducible clindamycin resistance	74	0.96	97	95
Daptomycin	74	0.37	96	96
Fosfomycin	74	0.63	76	77	112	0.76	100	100
Trimethoprim/Sulfamethoxazole	74	0.62	95	95	142	0.87	96	96	107	0.92	98	93
Linezolid	123	0.37	97	96					63	1.00	100	100
Tetracycline	74	0.94	97	97
Tigecycline	123	0.82	95	94	112	0.97	100	100
Chloramphenicol					121	0.90	99	99	107	1.00	98	98
Colistin					127	0.97	98	98
Meropenem					157	0.96	93	93	73	0.97	98	98
Imipenem					141	0.96	100	100
Ertapenem					112	0.97	99	99
Average all molecules		0.82	94	93		0.94	98	97		0.95	99	98

^a Total number of isolates tested by the molecule. ^b R1CA categorical agreement between Reader 1 and reference methods. ^c R2CA categorical agreement between Reader 1 and reference methods.