Table 2.

Predicted miRNA-miTS interactions using mintRULS and validation using experimental data in human. Strong Target: Upper quartile (>75th percentile), Moderate Target: Middle quartile (in between 25th and 75th percentile), and Weak Target: Lower quartile (<25th percentile).

miRNA	Target Gene	Results in Reference	mintRULS		Experimental Evidence
			Predictions (Quartile)	Classification	Cells/Tissues	Reference
hsa-miR-548ba	LIFR	Target	Upper	Strong Target	ovarian granulosa cells	[59]
	PTEN	Target	Upper	Strong Target
	NEO1	Target	Upper	Strong Target
hsa-miR-34a-5p	CLOCK	Target	Upper	Strong Target	SH-SY5Y cells	[60]
	CREB1	Target	Upper	Strong Target
	GRIA4	Target	Lower	Weak Target
	SMAD2	Target	Upper	Strong Target
	SMAD7	Target	Upper	Strong Target
hsa-miR-22	BMP-7/6	Target	Upper	Strong Target	Mouse primary kidney fibroblasts	[67]
hsa-miR-146a-3p	TRAF6	Target	Upper	Strong Target	Mouse Myeloid cells	[68]
	RIPK2	Target	Upper	Strong Target
hsa-miR-125b	CPSF6	Target	Upper	Strong Target	HEK-293T	[69]
	PARP1	Target	Middle	Moderate Target	HEK-293T cells	[70,71]
	p53	Target	Upper	Strong Target
	Beta-actin	Non-Target	Lower	Weak Target
18S RNA	gld-1:gfp	Non-Target	Lower	Weak Target	Caenorhabditis elegans	[72]